The following Big 12 players were selected in the 2017 NFL Draft.

First Round
Patrick Mahomes (Texas Tech), QB, Kansas City Chiefs

Second Round
Joe Mixon (Oklahoma), RB, Cincinnati Bengals

Third Round
Jordan Willis (K-State), OLB, Cincinnati Bengals
D'Onta Foreman (Texas), RB, Houston Texans
Rasul Douglas (West Virginia), CB, Philadelphia Eagles

Fourth Round
Dede Westbrook (Oklahoma), WR, Jacksonville Jaguars
Samaje Perine (Oklahoma), RB, Washington Redskins

Fifth Round
Shelton Gibson (West Virginia), WR, Philadelphia Eagles

Sixth Round
Jordan Evans (Oklahoma), LB, Cincinnati Bengals
Vincent Taylor (Oklahoma State), DT, Miami Dolphins

Seventh Round
Josh Carraway (TCU), OLB, Tennessee Titans
Elijah Lee (K-State), LB, Minnesota Vikings
Kyle Fuller (Baylor), C, Houston Texans
Chris Carson (Oklahoma State), RB, Seattle Seahawks