Missouri (2-1) set a school record with 744 yards of offense and tied a school record for most points scored while holding Western Illinois (1-2) to just one first down and 44 total yards. That outburst broke the previous record of 665 yards against Kansas in 1949.
The Tigers built a 42-0 halftime lead against the overmatched Leathernecks of the Football Championship Subdivision. Josey scored on rushes of 6, 21 and 68 yards, breaking his career high of 112 yards in the first quarter. He didn't play in the second half, missing a chance to top Devin West's school-record 319 yards against Kansas in 1998.
Wes Kemp caught two TDs for Missouri, and backup QB Jimmy Costello threw his first career touchdown in fourth-quarter mop-up duty.
Western Illinois quarterback Josh Hudson was just 4 for 15 for 20 yards with one interception for the Missouri Valley Conference school. He was sacked four times and harassed all night by a Missouri defense that only had one sack in an overtime road loss last week against Arizona State.
Bryce Flowers led Western Illinois with 28 yards rushing on 14 carries. He replaced starter Caulton Ray, who was suspended before the game for an unspecified violation of team rules. First-string left tackle Enock Presendieu was also suspended.
Franklin was 18 for 25 for 246 yards for Missouri, playing just two series in the second half before coach Gary Pinkel summoned Costello and later Ashton Glaser. Franklin threw touchdowns of 10 and 37 yards to Kemp and 30 yards to T.J. Moe.
Jared Culver had 11 carries for 86 yards and one touchdown in relief of Josey, with Greg White adding 10 carries for 36 yards. Josey carried the ball just 14 times, an average of nearly 19 yards per carry. He started his first game of the season after injuries to De'Vion Moore and Kendial Lawrence.
Missouri's 69 points matched a mark set against Kansas in 1969 and tied against Nevada in 2008. The Tigers' 69-point victory margin topped the previous record of 60 points versus Centre (Ky.) 83 years ago.
Missouri opens Big 12 Conference play next week with a visit to Norman and top-ranked Oklahoma. The Tigers upset the Sooners 36-27 last year in Columbia.