NORMAN, Okla. (AP) - Landry Jones threw for 425 yards and five touchdowns, Tony Jefferson fueled a second-quarter scoring surge with three interceptions and second-ranked Oklahoma geared up for its rivalry game against Texas next week by beating Ball State 62-6 on Saturday night.
Jones had touchdown passes of 64 yards to Ryan Broyles and 56 yards to Jaz Reynolds a minute apart in the third quarter during the second high-volume scoring stretch for the Sooners (4-0).
Ball State (3-2) didn't stand much of a chance after recovering an onside kick to open the game, then going three-and-out, particularly after Jefferson stopped three straight Cardinals drives with picks midway through the second quarter.
It was the second straight week the Sooners had an unimpressive start before taking control with 28 straight points in the second quarter.
Coach Bob Stoops had responded to last week's 38-28 victory against Missouri by increasing the intensity in practice and allowing more contact at the start of the week.
Led by Jefferson, the Sooners provided a resounding response, with little time left for tweaks before the Red River Rivalry in Dallas next Saturday.
Keith Wenning had gone 176 straight passes without an interception but then threw three to Jefferson in a span of four attempts, and Oklahoma capitalized to score 28 points in 5 1/2 minutes to turn a four-point game into a blowout.
On Ball State's first play after Dominique Whaley's 25-yard TD run, Sooners defensive end Frank Alexander tipped Wenning's pass high into the air, and Jefferson leaped to grab the ball. That set up Kenny Stills' 7-yard touchdown catch from Jones two plays later.
Jefferson ended Ball State's next drive by tipping Wenning's overthrown pass with his right hand and then corralling it along the Cardinals sideline. Roy Finch picked up 47 yards on a swing pass, and Whaley then punched it in with a 1-yard score on his fourth straight carry.
And Jefferson wasn't done yet.
He tracked down another batted ball - this time by R.J. Washington - for his third interception in a span of six offensive snaps by the Cardinals. Broyles scored two plays later on a 27-yard touchdown catch from Jones, capping the Sooners' sudden scoring spurt and make it 38-6.
Jefferson had a shot at picking off a pass on four straight drives, when Wenning's throw clipped off Toreial Gibson's hands and then off of Jefferson's before falling incomplete.
Tom Wort picked up where Jefferson left off, recovering Wenning's fumble and running it back 22 yards for a score that made it 59-6 with 11:34 left in the third quarter. That capped a 68-second span with three Oklahoma touchdowns, after the Sooners had already scored a pair of touchdowns 49 seconds apart twice in the first half.
Wenning, coming off a career-best 324-yard outing against Army last week, managed just 84 yards on 12-for-31 passing. The Cardinals were outgained 655-214.
The most trying times for the Sooners came early in the second quarter, just before the scoring onslaught.
Ball State got within 10-6 after a 15-play, 7-minute drive that finished with Steven Schott's second field goal of the game. Then Brennan Clay and Whaley, Oklahoma's top two running backs, both got dinged up within three plays.
While one group of trainers were helping Clay across the field, another group was helping Whaley remove his jersey so they could tend to his right shoulder. He returned six plays after Clay left, going for a 10-yard pickup before his 25-yard score around the left side.
Whaley finished with 109 yards on 15 carries, with most of the damage coming in the first half. Clay did not return.
Broyles caught four passes to move to 304 career receptions, one more than the previous Big 12 record set by Texas Tech running back Taurean Henderson (2002-05). He is 12 catches behind the NCAA career record held by Purdue's Taylor Stubblefield (2001-04).
Broyles had 109 yards receiving with two touchdowns. Reynolds had 141 yards on five catches.