"We sincerely thank Dan who has always demonstrated a total commitment to what is in the best interest of the Big 12 Conference," Missouri chancellor and chair of the board of directors Brady J. Deaton said in a statement. "His energy, devotion and skill in negotiating on our behalf have been tremendous assets that have benefited our member institutions, our student-athletes, our athletic programs and all our fans."
Deaton announced that the Conference has retained Chuck Neinas to serve as interim commissioner. Neinas will begin his duties next week.
"I have been honored to serve the Big 12 Conference," Beebe said in a statement. "I thank all those with whom I have worked over the years. I am especially grateful for the outstanding staff at the conference office who have dedicated so much for the sake of the Big 12.
"I care deeply for these fine institutions and the citizens they represent. It is satisfying to know the Big 12 Conference will survive, and I congratulate the members for taking strong action to ensure a bright future as a premier intercollegiate athletics conference."
Beebe joined the Big 12 staff in 2003 as senior associate commissioner. He was named commissioner in September of 2007.